Findings

What do systematic reviews say?

47 questions · 47 findings · 1 reviews · Injuries

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No studies found 0 · 0%GRADE not reported 2 · 4.3%Very low 7 · 14.9%Low 30 · 63.8%Moderate 8 · 17%High 0 · 0%

Intervention not reported

TXA given intravenously at a total dose of 1 g pre‐incision and intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
1 participants
Low

Intervention not reported

TXA given intravenously at a total dose of 1 g intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin) Comparator…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
1 participants
Low

Intervention not reported

TXA given intravenously at a total dose of 2 g pre‐incision · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
2 participants
Moderate

Intervention not reported

TXA given intravenously and intra‐articularly at a total dose of 2 g intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
2 participants
Moderate

Intervention not reported

TXA given intravenously and orally at a total dose of greater than 3 g pre‐incision and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
3 participants
Low

Intervention not reported

TXA given intravenously at a total dose of 1 g pre‐incision and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
1 participants
Low

Intervention not reported

TXA given intravenously and intra‐articularly at a total dose of greater than 3 g pre‐incision, intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…

1 finding from 1 review

Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes only
no estimate extracted
3 participants
Low