Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

76 questions · 76 findings · 18 reviews

No studies found 37 · 48.7%GRADE not reported 11 · 14.5%Very low 16 · 21.1%Low 10 · 13.2%Moderate 2 · 2.6%High 0 · 0%

Fibre-optic transillumination (FOTI) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Fibre-optic transillumination (FOTI) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Fibre-optic transillumination (FOTI, including white light scattering and near infrared) vs Reference standard: histology or enhanced visual-tactile examination

Outcome not reported · Adults presenting asymptomatically or suspected of having root caries (in vivo); extracted teeth of adults (in vitro)

The review found no eligible studies for this question.

1 finding from 1 review

Iodine vs non‐antibacterial

Wound healing · people with burns

It is very uncertain whether iodine changes wound healing (mean time to healing): iodine gauze versus carbon fibre compared with non‐antibacterial (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    MD 5.38 [3.09, 7.67]
    1 study · 277 participants
    Very low

Alternating pressure (active) air surfaces vs reactive fibre surfaces

Proportion of participants developing a new pressure ulcer · pressure ulcer prevention

It is very uncertain whether alternating pressure (active) air surfaces changes proportion of participants developing a new pressure ulcer compared with reactive fibre surfaces (very low certainty).

1 finding from 1 review