Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

78 questions · 79 findings · 19 reviews

No studies found 5 · 6.3%GRADE not reported 2 · 2.5%Very low 27 · 34.2%Low 18 · 22.8%Moderate 17 · 21.5%High 10 · 12.7%

Multiple vs fewer antiplatelet agents

Stroke, myocardial infarction, or vascular death · preventing early recurrence after ischaemic stroke or TIA

Multiple probably leads to lower stroke, myocardial infarction, or vascular death compared with fewer antiplatelet agents (moderate certainty).

1 finding from 1 review

Intervention not reported

Total studies: 93 Total participants: 22,558 · people with chronic pain Interventions: amitriptyline standard dose (25‐75 mg); desvenlafaxine high dose (> 50 mg); duloxetine low dose (<…

The intervention led to lower total studies: 93 Total participants: 22,558; GRADE not reported.

1 finding from 1 review