What do systematic reviews say?

Pulse cyclophosphamide vs continuous cyclophosphamide

Pulse cyclophosphamide showed no clear difference in death at final compared with continuous cyclophosphamide (low certainty).

• Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
  RR 0.77 [0.44, 1.32]
  4 studies · 278 participants
  Low

Pulse cyclophosphamide vs continuous cyclophosphamide

• Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 52 participants
  Low

CVVHD vs CVVH or CVVHDF

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher blood flow vs standard blood flow

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 499 participants
  Low

Higher blood flow vs standard blood flow

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher blood flow vs standard blood flow

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher blood flow vs standard blood flow

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Long (> 20 cm) vs short (≤ 20 cm) catheter

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 402 participants
  Low

Long (> 20 cm) vs short (≤ 20 cm) catheter

It is very uncertain whether long (> 20 cm) changes death from any cause at day 28 of compared with short (≤ 20 cm) catheter (very low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 1.38 [0.61, 3.11]
  1 study · 94 participants
  Very low

Long (> 20 cm) vs short (≤ 20 cm) catheter

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CVVHD vs CVVH or CVVHDF

It is very uncertain whether CVVHD changes death from any cause compared with CVVH or CVVHDF (very low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.77 [0.42, 1.4]
  4 studies · 229 participants
  Very low

Long (> 20 cm) vs short (≤ 20 cm) catheter

Long (> 20 cm) may leads to lower vascular access complications compared with short (≤ 20 cm) catheter (low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.38 [0.2, 0.72]
  1 study · 94 participants
  Low

Surface‐modified vs standard catheter

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 262 participants
  Low

Surface‐modified vs standard catheter

It is very uncertain whether surface‐modified changes death from any cause at day 28 of compared with standard double‐lumen catheter with identical geometry and flow design (very low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 1.08 [0.76, 1.53]
  1 study · 236 participants
  Very low

Surface‐modified vs standard catheter

Surface‐modified showed no clear difference in recovery of kidney function compared with standard double‐lumen catheter with identical geometry and flow design (low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.91 [0.7, 1.2]
  1 study · 236 participants
  Low

Surface‐modified vs standard catheter

Surface‐modified showed no clear difference in vascular access complications compared with standard double‐lumen catheter with identical geometry and flow design (low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.33 [0.09, 1.2]
  1 study · 236 participants
  Low

Polyethylenimine‐treated membrane (AN69ST) vs other membranes

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 56 participants
  Low