OHSS · anovulatory women with clomiphene citrate‐failure
1 finding from 1 review
Live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32 kg/m2 · women with polycystic ovary syndrome
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).
Live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (very low certainty).
Gastrointestinal adverse events · women with polycystic ovary syndrome
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Clinical pregnancy rate per woman Participants with BMI < 30 kg/m2 or ≤ 32 kg/m2a · women with polycystic ovary syndrome
Metformin may leads to higher clinical pregnancy rate per womanaParticipants with BMI < 30 kg/m2… compared with clomiphene citrate (low certainty).
Clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Ovulation rate per woman fParticipants with BMI < 30 kg/m2 · women with polycystic ovary syndrome
Metformin showed no clear difference in ovulation rate per woman fParticipants with BMI < 30 kg/m2 compared with clomiphene citrate (low certainty).
Ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Live birth rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ongoing pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in ongoing pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Miscarriage per clinical pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Clinical pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone may leads to higher clinical pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Multiple pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in multiple pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Live birth or ongoing pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in live birth rate/ongoing pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Miscarriage per clinical pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Clinical pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone may leads to higher clinical pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Multiple pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in multiple pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Adverse events, OHSS, preterm delivery, congenital anomaly · women with oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Miscarriage rate per woman aParticipants with BMI < 30 kg/2 · women with polycystic ovary syndrome
Metformin showed no clear difference in miscarriage rate per woman aParticipants with BMI < 30 kg/2 compared with clomiphene citrate (low certainty).
1 finding from 1 review