Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

119 questions · 127 findings · 15 reviews · Developmental, Psychosocial and Learning Problems

No studies found 23 · 18.1%GRADE not reported 8 · 6.3%Very low 28 · 22%Low 57 · 44.9%Moderate 11 · 8.7%High 0 · 0%

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

The review found no eligible studies for this question.

1 finding from 1 review

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Adverse effects · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

It is very uncertain whether attention deficit hyperactivity disorder (ADHD)‐related drugs changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Music therapy vs placebo or usual care

Global improvement · Individuals with autism spectrum disorder

Music therapy probably leads to higher global improvement compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review

Music therapy vs placebo or usual care

Adverse events Any serious or non‐serious adverse event · Individuals with autism spectrum disorder

Music therapy showed no clear difference in adverse events Any serious or non‐serious adverse event compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review