Findings

What do systematic reviews say?

50 questions · 50 findings · 3 reviews · Vascular

Sort:Best matchNewest Highest certainty Download CSV

No studies found 12 · 24%GRADE not reported 9 · 18%Very low 11 · 22%Low 9 · 18%Moderate 9 · 18%High 0 · 0%

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

All‐cause mortality · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Quality of life · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

Adverse events other than bleeding · people with antiphospholipid antibodies and no history of thrombosis

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported

Anticoagulant with or without ASA vs ASA only

Minor bleeding · people with antiphospholipid antibodies and no history of thrombosis

Anticoagulant with or without ASA may leads to higher bleeding ‐ minor (not requiring hospital admission) Median compared with ASA only (low certainty).

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
RR 22.45 [1.34, 374.81]
1 study · 164 participants
Low

Anticoagulant with or without ASA vs ASA only

All‐cause mortality · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Anticoagulant with or without ASA vs ASA only

Quality of life · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Anticoagulant with or without ASA vs ASA only

Adverse event other than bleeding · people with antiphospholipid antibodies and no history of thrombosis

Anticoagulant with or without ASA led to lower adverse event other than bleeding compared with ASA only; GRADE not reported.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
2014 participants
GRADE not reported

Aspirin vs placebo

Thrombosis · people with antiphospholipid antibodies and no history of thrombosis

ASA showed no clear difference in thrombosis compared with placebo (low certainty).

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
RR 5.21 [0.63, 42.97]
1 study · 98 participants
Low

Aspirin vs placebo

Major bleeding · people with antiphospholipid antibodies and no history of thrombosis

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 98 participants
GRADE not reported

Aspirin vs placebo

Minor bleeding · people with antiphospholipid antibodies and no history of thrombosis

ASA showed no clear difference in bleeding ‐ minor compared with placebo (low certainty).

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
RR 3.13 [0.34, 29.01]
1 study · 98 participants
Low