What do systematic reviews say?

Ibuprofen taken pre-emptively (about 1 hour before treatment) vs Ibuprofen taken post-treatment

The review found no eligible studies for this question.

• Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes
  No studies in this comparison reported any adverse events.
  0 studies
  No studies found

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

The review found no eligible studies for this question.

• Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
  None of the included studies assessed anxiety or behaviour at baseline, and none recorded baseline anxiety. PUB3: 'The [three/four] studies did not measure ... preoperative and postoperative anxiety measures ...'
  0 studies
  No studies found

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

The review found no eligible studies for this question.

• Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
  None of the included studies measured intraoperative pain. PUB3: 'The [three/four] studies did not measure intraoperative pain, ... cost or completion of treatment.'
  0 studies
  No studies found

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

The review found no eligible studies for this question.

• Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
  None of the included studies reported cost. PUB3: 'The [three/four] studies did not measure ... cost or completion of treatment.'
  0 studies
  No studies found

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

The review found no eligible studies for this question.

• Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
  None of the included studies measured completion of treatment. PUB3: 'The [three/four] studies did not measure intraoperative pain, preoperative and postoperative anxiety measures, patient satisfaction, parental…
  0 studies
  No studies found

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

The review found no eligible studies for this question.

• Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
  None of the included studies reported parental satisfaction. PUB3: 'there was no reporting of participant or parent satisfaction in any included study.'
  0 studies
  No studies found

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

The review found no eligible studies for this question.

• Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
  None of the included studies reported patient satisfaction. PUB3: 'there was no reporting of participant or parent satisfaction in any included study.'
  0 studies
  No studies found

Intraligamental injection local anaesthetic vs no treatment

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  Anand 2005 used the Venham Picture Scale but, owing to the split-mouth design, postoperative anxiety could not be compared between the LA and no-treatment sides
  1 study
  GRADE not reported

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes

  Up to 30 minutes postoperatively; parent-reported to first night
  Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
  1 study · 54 participants
  Very low

Intraligamental injection local anaesthetic vs no treatment

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  Anand 2005: no signs of postoperative soft tissue trauma, 21 children reported numbness on the LA (experimental) side; Sammons 2007: no adverse events reported
  2 studies
  GRADE not reported

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  The study did not report on patient or child satisfaction
  0 studies
  No studies found

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  None of the studies reported on this outcome
  0 studies
  No studies found

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  None of the studies reported on this outcome
  0 studies
  No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes

  Postoperatively, typically up to discharge (5 to 60 minutes)
  Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
  4 studies · 343 participants
  Very low

Infiltration injection local anaesthetic vs no treatment or placebo

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  Coulthard 2006: lip/cheek biting 3/70 (LA) vs 1/69 (placebo), P=0.62; Townsend 2009: 4/11 vs 1/12, P=0.16; no statistically significant difference
  2 studies · 162 participants
  GRADE not reported

Primary outcome: topical local anaesthetics vs placebo or no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  None of the studies reported on this outcome
  0 studies
  No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  None of the studies reported on lip or cheek biting
  0 studies
  No studies found

Infiltration injection local anaesthetic vs no treatment or placebo

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  No study reported parental satisfaction
  0 studies
  No studies found

Intraligamental injection local anaesthetic vs no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  None of the studies reported on this outcome
  0 studies
  No studies found

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

The review found no eligible studies for this question.

• Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
  No study reported parental satisfaction
  0 studies
  No studies found