Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

51 questions · 54 findings · 8 reviews

No studies found 12 · 22.2%GRADE not reported 0 · 0%Very low 5 · 9.3%Low 6 · 11.1%Moderate 22 · 40.7%High 9 · 16.7%

Intervention not reported

OutcomesAnalysis 1.4 · Patients with active Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Failure to achieve clinical remission · Patients with active Crohn's disease

The intervention leads to lower failure to achieve clinical remission (high certainty).

1 finding from 1 review

Intervention not reported

Failure to achieve clinical response (70‐point response) · Patients with active Crohn's disease

The intervention leads to lower failure to achieve clinical response (70‐point response) (high certainty).

1 finding from 1 review

Intervention not reported

Failure to achieve clinical response (100‐point response) · Patients with active Crohn's disease

The intervention leads to lower failure to achieve clinical response (100‐point response) (high certainty).

1 finding from 1 review

Intervention not reported

Endoscopic response · Patients with active Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life (QoL) Inflammatory Bowel Disease Questionnaire (IBDQ) (scale: 32 to 224; higher score = better QoL) · Patients with active Crohn's disease
1 finding from 1 review

Intervention not reported

Adverse events · Patients with active Crohn's disease

The intervention showed no clear difference in adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · Patients with active Crohn's disease

The intervention showed no clear difference in serious adverse events (low certainty).

1 finding from 1 review

Intervention not reported

Withdrawals due to adverse events · Patients with active Crohn's disease

The intervention showed no clear difference in withdrawals due to adverse events (low certainty).

1 finding from 1 review