What do systematic reviews say?

Finasteride 5 mg vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Finasteride 5 mg showed no clear difference in participant‐reported improvement of hirsutism 4‐point Likert scale compared with flutamide 250 mg once to b.i.d. (low certainty).

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  RR 0.63 [0.31, 1.25]
  1 study · 20 participants
  Low

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

It is very uncertain whether finasteride 5 mg changes proportion of participants who reported an adverse event compared with flutamide 250 mg once to b.i.d. (very low certainty).

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  RR 3.87 [0.57, 26.24]
  3 studies · 115 participants
  Very low

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 226 participants
  Very low

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 226 participants
  Moderate

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 110 participants
  High

Levocetirizine 5 to 20 mg vs placebo

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Low

Hydroxyzine 25 mg vs placebo

Hydroxyzine 25 mg showed no clear difference in adverse events leading to withdrawal: intermediate‐term duration of… compared with placebo (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 3.64 [0.77, 17.23]
  2 studies · 270 participants
  Low

Desloratadine 5 to 20 mg vs placebo

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 46 participants
  Low

Desloratadine 5 to 20 mg vs placebo

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 80 participants
  Low

Desloratadine 5 to 20 mg vs placebo

Desloratadine 5 to 20 mg showed no clear difference in adverse effects leading to withdrawal: intermediate‐term duration of… compared with placebo (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 1.46 [0.42, 5.1]
  3 studies · 466 participants
  Low

Levocetirizine 5 to 20 mg vs placebo

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Low

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg showed no clear difference in proportion of participants who reported an adverse event compared with ethinyl estradiol 30 μg + desogestrel 0.15 mg (moderate certainty).

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  RR 0.41 [0.08, 2.05]
  1 study · 100 participants
  Moderate

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 164 participants
  Low

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 184 participants
  High

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found