C2: Neurodevelopmental impairment at early childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C2: Neurodevelopmental impairment at early childhood compared with single course (high certainty).
1 finding from 1 review
C3: Survival free of neurodevelopmental impairment at early childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C3: Survival free of neurodevelopmental impairment at early childhood compared with single course (high certainty).
1 finding from 1 review
C4: Survival free of major neurodevelopmental impairment atearly childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C4: Survival free of major neurodevelopmental impairment atearly… compared with single course (moderate certainty).
1 finding from 1 review
D1: Total deaths (after randomisation) up to mid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D1: Total deaths (after randomisation) up to mid‐ to later childhood compared with single course (moderate certainty).
1 finding from 1 review
Respiratory distress syndrome · the fetus/neonate/infant
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid leads to lower A5: Respiratory distress syndrome – all fetuses randomised compared with single course (high certainty).
1 finding from 1 review
D2: Neurocognitive impairment atmid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D2: Neurocognitive impairment atmid‐ to later childhood compared with single course (low certainty).
1 finding from 1 review
D3: Survival free of neurocognitive impairment atmid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D3: Survival free of neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).
1 finding from 1 review
D4: Survival free of major neurocognitive impairment atmid‐ to later childhood · the child
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in D4: Survival free of major neurocognitive impairment atmid‐ to later… compared with single course (moderate certainty).
1 finding from 1 review
A7: Severe lung disease – all fetuses randomised · the fetus/neonate/infant
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid probably leads to lower A7: Severe lung disease – all fetuses randomised compared with single course (moderate certainty).
1 finding from 1 review
Chronic lung disease · the fetus/neonate/infant
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A8: Chronic lung disease – all fetuses randomised compared with single course (high certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · the fetus/neonate/infant
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A9: Severe intraventricular haemorrhage (grade 3 or 4) – all fetuses… compared with single course (moderate certainty).
1 finding from 1 review
Necrotising enterocolitis · the fetus/neonate/infant
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A11: Necrotising enterocolitis – all fetuses randomised compared with single course (moderate certainty).
1 finding from 1 review
A12: Composite of serious outcomes– all fetuses randomised · the fetus/neonate/infant
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid probably leads to lower A12: Composite of serious outcomes– all fetuses randomised compared with single course (moderate certainty).
1 finding from 1 review
Maternal death · the woman
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B1: Maternal death – all women compared with single course (low certainty).
1 finding from 1 review
B2: Maternal sepsis – an all women · the woman
Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B2: Maternal sepsis – an all women compared with single course (moderate certainty).
1 finding from 1 review
Preterm birth less than 34 weeks' gestation · women with singleton pregnancies at risk of cervical insufficiency
Cervical pessary showed no clear difference in delivery before 34 weeks' gestation compared with no treatment (low certainty).
1 finding from 1 review
Maternal infection or inflammation · women with singleton pregnancies at risk of cervical insufficiency
Cervical pessary showed no clear difference in maternal infection or inflammation compared with vaginal progesterone (moderate certainty).
1 finding from 1 review
Neonatal/paediatric care unit admission · women with singleton pregnancies at risk of cervical insufficiency
Cervical pessary showed no clear difference in neonatal/paediatric care unit admission compared with vaginal progesterone (low certainty).
1 finding from 1 review
Fetal/infant mortality · women with singleton pregnancies at risk of cervical insufficiency
Cervical pessary showed no clear difference in fetal/infant mortality compared with vaginal progesterone (low certainty).
1 finding from 1 review
Harm to offspring from the intervention · women with singleton pregnancies at risk of cervical insufficiency
1 finding from 1 review