Ureteral obstruction · primary VUR
Macroplastique showed no clear difference in ureteral obstruction compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
1 finding from 1 review
Post operative flank pain · primary VUR
Macroplastique showed no clear difference in post operative flank pain compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
1 finding from 1 review
New renal parenchymal defects on DMSA scan (kidney injury) · primary VUR
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with symptomatic UTI · primary VUR
Probiotics showed no clear difference in all symptomatic UTI by 1 year compared with antibiotic prophylaxis (low certainty).
1 finding from 1 review
Febrile UTI by 1 year · primary VUR
Probiotics showed no clear difference in febrile UTI by 1 year compared with antibiotic prophylaxis (low certainty).
1 finding from 1 review
E. coli resistance to prophylactic drug · primary VUR
Probiotics may leads to lower E. coli resistance to prophylactic drug compared with antibiotic prophylaxis (low certainty).
1 finding from 1 review
Renal parenchymal defects on DMSA scan ‐ Patient data at 1 year · primary VUR
Probiotics showed no clear difference in renal parenchymal defects on DMSA scan ‐ Patient data at 1 year compared with antibiotic prophylaxis (low certainty).
1 finding from 1 review
Resolution of VUR · primary VUR
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · primary VUR
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of VUR · primary VUR
Antibiotic prophylaxis showed no clear difference in resolution of VUR after 1 to 2 years: unit of analysis (children) compared with surveillance or no treatment (low certainty).
1 finding from 1 review
Adverse events · primary VUR
Antibiotic prophylaxis showed no clear difference in adverse events compared with surveillance or no treatment (moderate certainty).
1 finding from 1 review
Microbial resistance to prophylactic drug: unit of analysis (UTI) · primary VUR
Antibiotic prophylaxis probably leads to higher microbial resistance to prophylactic drug: unit of analysis (UTI) compared with surveillance or no treatment (moderate certainty).
1 finding from 1 review
Number of participants with symptomatic UTI · primary VUR
Surgical reimplantation of ureters plus antibiotics showed no clear difference in all symptomatic UTI by 4 to 5 years: surgical correction +… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Febrile UTI by 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR
Surgical reimplantation of ureters plus antibiotics probably leads to lower febrile UTI by 5 years: surgical correction + antibiotics versus… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Repeat positive urine culture · primary VUR
Surgical reimplantation of ureters plus antibiotics showed no clear difference in repeat positive urine cultures by 4 to 5 years: surgical correction… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
Complete remission: all renal pathologies · idiopathic steroid‐resistant nephrotic syndrome in children
Cyclosporin may leads to higher complete remission: all renal pathologies compared with placebo or no treatment (low certainty).
1 finding from 1 review
Partial remission ( · idiopathic steroid‐resistant nephrotic syndrome in children
It is very uncertain whether calcineurin inhibitor changes treatment response at 3 to 6 months: partial remission compared with IV cyclophosphamide (very low certainty).
1 finding from 1 review
Adverse events: treatment failure (non response, serious infection, persistently elevated creatinine) at 6 months · idiopathic steroid‐resistant nephrotic syndrome in children
Calcineurin inhibitor probably leads to lower adverse events: treatment failure at 6 months (non response, serious… compared with IV cyclophosphamide (moderate certainty).
1 finding from 1 review
Discontinuation of medication due to adverse events · idiopathic steroid‐resistant nephrotic syndrome in children
Calcineurin inhibitor probably leads to lower adverse events: medications ceased due to adverse events compared with IV cyclophosphamide (moderate certainty).
1 finding from 1 review
Adverse events: serious infections · idiopathic steroid‐resistant nephrotic syndrome in children
Calcineurin inhibitor showed no clear difference in adverse events: serious infections compared with IV cyclophosphamide (moderate certainty).
1 finding from 1 review