Findings

What do systematic reviews say?

625 questions · 659 findings · 70 reviews

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No studies found 129 · 19.6%GRADE not reported 71 · 10.8%Very low 210 · 31.9%Low 170 · 25.8%Moderate 79 · 12%High 0 · 0%

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Cognitive function · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Post‐treatment quality of life (QOLIE‐31 score, which has a range of 0‐200, with higher score indicates better quality of life) ( · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
15 participants
Very low

Selective serotonin reuptake inhibitors vs cognitive behavioural therapy

Adverse effects ‐ adverse event profile · people with epilepsy and depression

1 finding from 1 review

Antidepressants for people with epilepsy and depression 2021 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Severity of PTSD symptoms · adults aged ≥ 16 years with PTSD

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Leaving the study early · adults aged ≥ 16 years with PTSD

It is very uncertain whether internet‐based cognitive and behavioural therapy (I‐C/BT) changes dropouts compared with face‐to‐face non‐CBT (very low certainty).

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
RR 2.49 [0.91, 6.77]
1 study · 40 participants
Very low

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Diagnosis of PTSD after treatment · adults aged ≥ 16 years with PTSD

The review found no eligible studies for this question.

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Depressive symptoms · adults aged ≥ 16 years with PTSD

The review found no eligible studies for this question.

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Anxiety · adults aged ≥ 16 years with PTSD

The review found no eligible studies for this question.

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Cost‐effectiveness · adults aged ≥ 16 years with PTSD

The review found no eligible studies for this question.

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT

Adverse events · adults aged ≥ 16 years with PTSD

The review found no eligible studies for this question.

1 finding from 1 review

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Behavioural activation vs CBT

treatment efficacyup to 6 months (5‐12 weeks) · depression in adults

Behavioural activation showed no clear difference in treatment efficacyup to 6 months (5‐16 weeks) compared with CBT (moderate certainty).

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
RR 0.99 [0.92, 1.07]
5 studies · 601 participants
Moderate

Behavioural activation vs third‐wave CBT

depression symptoms (continuous) up to 6 months (4‐8 weeks) · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 147 participants
Low

Behavioural activation vs third‐wave CBT

quality of life (continuous)up to 6 months (8 weeks) · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 81 participants
Low

Behavioural activation vs third‐wave CBT

Anxiety · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 147 participants
Low

Behavioural activation vs CBT

Secondary outcome: acceptability of treatment · depression in adults

Behavioural activation showed no clear difference in treatment acceptability up to 6 months (4‐16 weeks) compared with CBT (low certainty).

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
RR 1.03 [0.85, 1.25]
12 studies · 1195 participants
Low

Behavioural activation vs CBT

depression symptoms (continuous) up to 6 months (4‐16 weeks) · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 1205 participants
Moderate

Behavioural activation vs CBT

quality of life (continuous)up to 6 months (8 weeks) · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 268 participants
Moderate

Behavioural activation vs CBT

social adjustment and functioning (continuous)up to 6 months (12 weeks) · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 111 participants
Very low

Behavioural activation vs CBT

Anxiety · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 646 participants
Moderate

Behavioural activation vs CBT

adverse events (16 weeks) · depression in adults

1 finding from 1 review

Behavioural activation therapy for depression in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 398 participants
Moderate