Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

761 questions · 801 findings · 50 reviews · Common Mental Disorders

No studies found 125 · 15.6%GRADE not reported 34 · 4.2%Very low 226 · 28.2%Low 232 · 29%Moderate 176 · 22%High 8 · 1%

Intervention not reported

Depressive symptoms at the end of treatment Beck Depression Inventory (BDI) or Hamilton Depression Rating Scale (HDRS). BDI is a self‐report inventory including 21 questions, each answer being scored from 0 to 3 with the total score ranging from 0... · heterosexual adult couples aged > 18 with a partner having a clinical diagnosis of depressive disorder
1 finding from 1 review

Client feedback vs no client feedback

Treatment acceptability: dropouts from treatment · children and adolescents, 11 to 18 years old, with mental health problems

It is very uncertain whether client feedback changes treatment acceptability: dropouts from treatment compared with no client feedback (very low certainty).

1 finding from 1 review

Comparison 1: 5HT1A partial agonists vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults with SAnD

It is very uncertain whether comparison 1: 5HT1A partial agonists changes global Impressions scale change item (CGI‐I or similar): no. of… compared with placebo (very low certainty).

1 finding from 1 review

Levetiracetam vs placebo

Withdrawals due to adverse events · adults with SAnD

It is very uncertain whether comparison 3: anticonvulsant levetiracetam changes dropouts due to adverse events (acute phase) compared with placebo (very low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults with SAnD

It is very uncertain whether comparison 4: antipsychotics changes global Impressions scale change item (CGI‐I or similar): no. of… compared with placebo (very low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Withdrawals due to adverse events · adults with SAnD

It is very uncertain whether comparison 4: antipsychotics changes dropouts due to adverse events (acute phase) compared with placebo (very low certainty).

1 finding from 1 review

Benzodiazepines vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults with SAnD

Comparison 5: benzodiazepines may leads to higher global Impressions scale change item (CGI‐I or similar): no. of… compared with placebo (low certainty).

1 finding from 1 review

Benzodiazepines vs placebo

Withdrawals due to adverse events · adults with SAnD

It is very uncertain whether comparison 5: benzodiazepines changes dropouts due to adverse events (acute phase) compared with placebo (very low certainty).

1 finding from 1 review