Macroplastique probably leads to lower number of ureters with persistent VUR > grade 1 at 1 year compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (moderate certainty).
Macroplastique may leads to higher number of kidneys with temporary renal dilatation after injection compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
Macroplastique showed no clear difference in ureteral obstruction compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
Macroplastique showed no clear difference in post operative flank pain compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
The review found no eligible studies for this question.
Probiotics showed no clear difference in all symptomatic UTI by 1 year compared with antibiotic prophylaxis (low certainty).
Probiotics showed no clear difference in febrile UTI by 1 year compared with antibiotic prophylaxis (low certainty).
Probiotics may leads to lower E. coli resistance to prophylactic drug compared with antibiotic prophylaxis (low certainty).
Probiotics showed no clear difference in renal parenchymal defects on DMSA scan ‐ Patient data at 1 year compared with antibiotic prophylaxis (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Antibiotic prophylaxis showed no clear difference in resolution of VUR after 1 to 2 years: unit of analysis (children) compared with surveillance or no treatment (low certainty).
Antibiotic prophylaxis showed no clear difference in adverse events compared with surveillance or no treatment (moderate certainty).
Antibiotic prophylaxis probably leads to higher microbial resistance to prophylactic drug: unit of analysis (UTI) compared with surveillance or no treatment (moderate certainty).
Surgical reimplantation of ureters plus antibiotics showed no clear difference in all symptomatic UTI by 4 to 5 years: surgical correction +… compared with antibiotics alone (moderate certainty).
Surgical reimplantation of ureters plus antibiotics probably leads to lower febrile UTI by 5 years: surgical correction + antibiotics versus… compared with antibiotics alone (moderate certainty).
Surgical reimplantation of ureters plus antibiotics showed no clear difference in repeat positive urine cultures by 4 to 5 years: surgical correction… compared with antibiotics alone (moderate certainty).
Cyclosporin may leads to higher complete remission: all renal pathologies compared with placebo or no treatment (low certainty).
It is very uncertain whether calcineurin inhibitor changes treatment response at 3 to 6 months: partial remission compared with IV cyclophosphamide (very low certainty).
Calcineurin inhibitor probably leads to lower adverse events: treatment failure at 6 months (non response, serious… compared with IV cyclophosphamide (moderate certainty).