The review found no eligible studies for this question.
Unfractionated heparin showed no clear difference in major bleeding compared with low molecular weight heparin (low certainty).
It is very uncertain whether unfractionated heparin changes death: unknown time frame compared with low molecular weight heparin (very low certainty).
Antibiotic prophylaxis showed no clear difference in symptomatic UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
Surgical reimplantation of ureters plus antibiotics showed no clear difference in new renal parenchymal defects (scars and thinning) on IVP: unit of… compared with antibiotics alone (moderate certainty).
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes ESKD compared with antibiotics alone (very low certainty).
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes hypertension compared with antibiotics alone (very low certainty).
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes correction of VUR: unit of analysis (children) after 3 years:… compared with antibiotics alone (very low certainty).
The review found no eligible studies for this question.
Endoscopic injection treatment showed no clear difference in all symptomatic UTI by 1 to 2 years: endoscopic correction +… compared with antibiotics alone (low certainty).
Endoscopic injection treatment showed no clear difference in febrile UTI by 1 to 2 years: endoscopic correction + antibiotics… compared with antibiotics alone (low certainty).
It is very uncertain whether endoscopic injection treatment changes repeat positive urine culture by 1 year compared with antibiotics alone (very low certainty).
Endoscopic injection treatment showed no clear difference in total new and progressive Renal parenchymal abnormalities on DMSA… compared with antibiotics alone (low certainty).
Endoscopic injection treatment may leads to higher resolution of VUR (grade 0) for endoscopic correction + antibiotics… compared with antibiotics alone (low certainty).
Antibiotic prophylaxis showed no clear difference in febrile UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
It is very uncertain whether endoscopic injection treatment changes microbial resistance to the prophylactic drug compared with antibiotics alone (very low certainty).
Macroplastique showed no clear difference in number of children with febrile UTI compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
Macroplastique showed no clear difference in number of children with afebrile UTI compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).
Macroplastique probably leads to lower number of ureters with persistent VUR > grade 1 at 1 year compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (moderate certainty).
Macroplastique may leads to higher number of kidneys with temporary renal dilatation after injection compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).