Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

662 questions · 720 findings · 164 reviews

No studies found 177 · 24.6%GRADE not reported 126 · 17.5%Very low 144 · 20%Low 139 · 19.3%Moderate 107 · 14.9%High 27 · 3.8%

Any Psychosocial intervention plus pharm vs pharm standard

Opioid abstinence objective · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in opioid abstinence objective compared with pharm standard (high certainty).

1 finding from 1 review

NBI + WLC TURBT vs WLC TURBT

Time to recurrence · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer

NBI + WLC TURBT may leads to lower time to disease recurrence compared with WLC TURBT (low certainty).

1 finding from 1 review

NBI + WLC TURBT vs WLC TURBT

Clavien‐Dindo grade ≥ 3 complications · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer

NBI + WLC TURBT showed no clear difference in major adverse event (Clavien‐Dindo grade III, IV, and V) compared with WLC TURBT (low certainty).

1 finding from 1 review

NBI + WLC TURBT vs WLC TURBT

Clavien‐Dindo grade ≤ 2 complications8 · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer

NBI + WLC TURBT showed no clear difference in minor adverse event (Clavien‐Dindo grade I and II) compared with WLC TURBT (low certainty).

1 finding from 1 review

IRI with fluoropyrimidines vs single agent IRI

Progression‐free survival (PSF) · patients with advanced and/or metastatic colorectal cancer

IRI with fluoropyrimidines probably leads to lower progression‐free survival (Disease progression) compared with single agent IRI (moderate certainty).

1 finding from 1 review

Intervention not reported

Lymph node mets analysis ‐ N+ OS · patients with resectable gastric cancer

The intervention probably leads to lower lymph node mets analysis ‐ N+ OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased OS ‐ 5‐FU based chemotherapy OS · patients with resectable gastric cancer

The intervention probably leads to lower chemobased OS ‐ 5‐FU based chemotherapy OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased OS ‐ Platinum‐based chemotherapy OS · patients with resectable gastric cancer

The intervention showed no clear difference in chemobased OS ‐ Platinum‐based chemotherapy OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased DFS ‐ 5‐FU based chemotherapy DFS · patients with resectable gastric cancer

The intervention probably leads to lower chemobased DFS ‐ 5‐FU based chemotherapy DFS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased DFS ‐ Platinum‐based chemotherapy DFS · patients with resectable gastric cancer

The intervention showed no clear difference in chemobased DFS ‐ Platinum‐based chemotherapy DFS (moderate certainty).

1 finding from 1 review

Intervention not reported

Stage OS analysis ‐ T1/2 OS · patients with resectable gastric cancer

The intervention showed no clear difference in stage OS analysis ‐ T1/2 OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Stage OS analysis ‐ T3/4 OS · patients with resectable gastric cancer

The intervention showed no clear difference in stage OS analysis ‐ T3/4 OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Lymph node mets analysis ‐ N‐ OS · patients with resectable gastric cancer

The intervention showed no clear difference in lymph node mets analysis ‐ N‐ OS (moderate certainty).

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Pocket closure · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
2 findings from 1 review