Findings

What do systematic reviews say?

510 questions · 513 findings · 62 reviews · Headline outcomes only

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No studies found 96 · 18.7%GRADE not reported 13 · 2.5%Very low 181 · 35.3%Low 121 · 23.6%Moderate 69 · 13.5%High 33 · 6.4%

Reablement vs usual home‐care

Living arrangements (transferred to residential care) · adults aged ≥ 65 years

1 finding from 1 review

Time‐limited home‐care reablement services for maintaining and improving the functional independence of older adults 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 750 participants
Very low

Reablement vs usual home‐care

Cost effectiveness*** Total aggregated costs for home‐ and healthcare (emergency department and unplanned hospital admissions) · adults aged ≥ 65 years

1 finding from 1 review

Time‐limited home‐care reablement services for maintaining and improving the functional independence of older adults 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 750 participants
Very low

Paroxetine vs older ADs

Failure to respond at endpoint (6‐12 weeks) · patients with depression

Paroxetine showed no clear difference in failure to respond at endpoint (6‐12 weeks) compared with older ADs (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.04 [0.92, 1.17]
34 studies · 4647 participants
Moderate

Paroxetine vs older ADs

Failure to respond at 1‐4 weeks · patients with depression

Paroxetine showed no clear difference in failure to respond at 1‐4 weeks compared with older ADs (low certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.9 [0.61, 1.33]
4 studies · 526 participants
Low

Paroxetine vs older ADs

Failure to respond at 16‐24 weeks · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs older ADs

Failure to remit at endpoint · patients with depression

Paroxetine showed no clear difference in failure to remit at endpoint compared with older ADs (low certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.23 [0.49, 3.07]
3 studies · 401 participants
Low

Paroxetine vs older ADs

SMD at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
35 studies · 4745 participants
Moderate

Paroxetine vs older ADs

Failure to complete ‐ any cause ‐ · patients with depression

Paroxetine probably leads to lower failure to complete ‐ any cause ‐ compared with older ADs (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.84 [0.73, 0.96]
44 studies · 6810 participants
Moderate

Paroxetine vs older ADs

Participants with at least some Side Effects · patients with depression

Paroxetine probably leads to lower participants with at least some Side Effects compared with older ADs (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.64 [0.54, 0.77]
42 studies · 6132 participants
Moderate

Supplementary feeding vs no food supplementation

Change in height-for-age z score · Children older than 24 months

1 finding from 1 review

Community‐based supplementary feeding for promoting the growth of children under five years of age in low and middle… 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 348 participants
Low