Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

754 questions · 769 findings · 35 reviews · Kidney and Transplant

No studies found 228 · 29.6%GRADE not reported 3 · 0.4%Very low 215 · 28%Low 245 · 31.9%Moderate 74 · 9.6%High 4 · 0.5%

Endoscopic injection treatment vs antibiotics alone

Febrile UTI by 1 to 2 years: endoscopic correction + antibiotics versus antibiotics alone · primary VUR

Endoscopic injection treatment showed no clear difference in febrile UTI by 1 to 2 years: endoscopic correction + antibiotics… compared with antibiotics alone (low certainty).

1 finding from 1 review

Endoscopic injection treatment vs antibiotics alone

Total new and progressive Renal parenchymal abnormalities on DMSA scan at 1 to 2 years: endoscopic correction + antibiotics versus antibiotics alone (unit of analysis: children) · primary VUR

Endoscopic injection treatment showed no clear difference in total new and progressive Renal parenchymal abnormalities on DMSA… compared with antibiotics alone (low certainty).

1 finding from 1 review

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Number of ureters with persistent VUR > grade 1 at 1 year · primary VUR

Macroplastique probably leads to lower number of ureters with persistent VUR > grade 1 at 1 year compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (moderate certainty).

1 finding from 1 review

Macroplastique vs dextranomer/hyaluronic acid polymer (Deflux) to correct vesicoureteric reflux

Number of kidneys with temporary renal dilatation after injection · primary VUR

Macroplastique may leads to higher number of kidneys with temporary renal dilatation after injection compared with dextranomer/hyaluronic acid polymer (Deflux) to correct… (low certainty).

1 finding from 1 review

Probiotics vs antibiotic prophylaxis

Renal parenchymal defects on DMSA scan ‐ Patient data at 1 year · primary VUR

Probiotics showed no clear difference in renal parenchymal defects on DMSA scan ‐ Patient data at 1 year compared with antibiotic prophylaxis (low certainty).

1 finding from 1 review