Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

505 questions · 512 findings · 67 reviews

No studies found 104 · 20.3%GRADE not reported 27 · 5.3%Very low 107 · 20.9%Low 129 · 25.2%Moderate 107 · 20.9%High 38 · 7.4%

Loratadine 10 mg vs desloratadine 5 mg

Good or excellent response: intermediate‐term duration of intervention Global assessment of symptom scores · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in good or excellent response: intermediate‐term duration of… compared with desloratadine 5 mg (low certainty).

1 finding from 1 review

Loratadine 10 mg vs hydroxyzine 25 mg

Complete suppression of urticaria: short‐term duration of intervention Global assessment of symptom scores · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in complete suppression of urticaria: short‐term duration of… compared with hydroxyzine 25 mg (low certainty).

1 finding from 1 review

Keratinocyte GF 50 mg vs Keratinocyte GF 25 mg

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Keratinocyte GF 50 mg showed no clear difference in oral mucositis (moderate to severe) compared with keratinocyte GF 25 mg; GRADE not reported.

1 finding from 1 review

Keratinocyte GF 50 mg vs Keratinocyte GF 25 mg

Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Keratinocyte GF 50 mg showed no clear difference in oral mucositis (severe) compared with keratinocyte GF 25 mg; GRADE not reported.

1 finding from 1 review