Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

583 questions · 638 findings · 60 reviews · Infectious Diseases

No studies found 54 · 8.5%GRADE not reported 98 · 15.4%Very low 118 · 18.5%Low 141 · 22.1%Moderate 141 · 22.1%High 86 · 13.5%

Mefloquine vs atovaquone‐proguanil

Discontinuation of medication due to adverse events · non‐immune adults and children travelling to or living in malaria‐endemic settings

Mefloquine led to higher discontinuation of drug due to adverse effects compared with atovaquone‐proguanil; GRADE not reported.

1 finding from 1 review

Intervention not reported

Clinical malaria (incidence) · people living in malaria‐endemic areas

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Entomological inoculation rate · people living in malaria‐endemic areas

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Density of adult malaria vectors · people living in malaria‐endemic areas

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Density of immature vector stages in water bodies Quasi‐experimental studies · people living in malaria‐endemic areas
1 finding from 1 review