Major bleeding · CRRT
It is very uncertain whether unfractionated heparin changes major bleeding compared with no pharmacological anticoagulation (very low certainty).
1 finding from 1 review
Death at 28 days · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Successful prevention of clotting · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment cessation due to adverse events · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recovery of kidney function · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death at 28 days · CRRT
Citrate showed no clear difference in death at 28 days compared with unfractionated heparin (moderate certainty).
1 finding from 1 review
Thrombocytopenia · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cost to health care services · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Successful prevention of clotting · CRRT
Citrate probably leads to higher successful prevention of clotting compared with unfractionated heparin (moderate certainty).
1 finding from 1 review
Treatment cessation due to adverse events · CRRT
Citrate showed no clear difference in treatment cessation due to adverse events compared with unfractionated heparin (low certainty).
1 finding from 1 review
Recovery of kidney function · CRRT
Citrate showed no clear difference in recovery of kidney function compared with unfractionated heparin (low certainty).
1 finding from 1 review
Thrombocytopenia · CRRT
Citrate showed no clear difference in thrombocytopenia compared with unfractionated heparin (low certainty).
1 finding from 1 review
Cost to health care services · CRRT
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Major bleeding · CRRT
Unfractionated heparin showed no clear difference in major bleeding compared with low molecular weight heparin (low certainty).
1 finding from 1 review
Death: unknown time frame · CRRT
It is very uncertain whether unfractionated heparin changes death: unknown time frame compared with low molecular weight heparin (very low certainty).
1 finding from 1 review
Number of participants with symptomatic UTI · primary VUR
Antibiotic prophylaxis showed no clear difference in symptomatic UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).
2 findings from 1 review
New renal parenchymal defects (scars and thinning) on IVP: unit of analysis (children) at 4 to 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR
Surgical reimplantation of ureters plus antibiotics showed no clear difference in new renal parenchymal defects (scars and thinning) on IVP: unit of… compared with antibiotics alone (moderate certainty).
1 finding from 1 review
ESKD · primary VUR
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes ESKD compared with antibiotics alone (very low certainty).
1 finding from 1 review
Hypertension · primary VUR
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes hypertension compared with antibiotics alone (very low certainty).
1 finding from 1 review
Correction of VUR: unit of analysis (children) after 3 years: surgical correction + antibiotics versus antibiotics alone · primary VUR
It is very uncertain whether surgical reimplantation of ureters plus antibiotics changes correction of VUR: unit of analysis (children) after 3 years:… compared with antibiotics alone (very low certainty).
1 finding from 1 review