Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

954 questions · 963 findings · 130 reviews · Headline outcomes only

No studies found 181 · 18.8%GRADE not reported 71 · 7.4%Very low 163 · 16.9%Low 311 · 32.3%Moderate 163 · 16.9%High 74 · 7.7%

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Apgar score less than 7 at 5 minutes · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in 5‐minute Apgar score < 7 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Low umbilical artery pH (< 7.2 or as defined by trial authors) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline showed no clear difference in umbilical artery pH < 7.2 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for IV hexoprenaline vs no tocolytic agent, whilst awaiting emergency delivery

Abnormal FHR as defined by trial authors (FHR tracing not improved) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

Summary of findings for IV hexoprenaline probably leads to lower FHR tracing not improved compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs IV magnesium sulphate

Low umbilical artery pH (< 7.2 or as defined by trial authors) · women for whom a decision had been made to deliver by caesarean section for suspected fetal distress based on FHR monitoring

It is very uncertain whether summary of findings for subcutaneous terbutaline changes umbilical artery pH < 7.2 compared with IV magnesium sulphate (very low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline with continuation of oxytocic infusion vs cessation of oxytocic infusion without tocolytic agent

Perinatal death or severe morbidity · women who developed uterine hyperstimulation in labour with oxytocin augmentation, but without signs of fetal distress

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for subcutaneous terbutaline with continuation of oxytocic infusion vs cessation of oxytocic infusion without tocolytic agent

Caesarean section · women who developed uterine hyperstimulation in labour with oxytocin augmentation, but without signs of fetal distress

Summary of findings for subcutaneous terbutaline with continuation… showed no clear difference in caesarean delivery compared with cessation of oxytocic infusion without tocolytic agent (low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline with continuation of oxytocic infusion vs cessation of oxytocic infusion without tocolytic agent

Abnormal FHR tracing · women who developed uterine hyperstimulation in labour with oxytocin augmentation, but without signs of fetal distress

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs no tocolytic agent, whilst awaiting emergency delivery

Perinatal death or severe morbidity · women in labour with signs of fetal distress and a fetal scalp pH < 7.25, for whom the decision had been made for emergency delivery

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs no tocolytic agent, whilst awaiting emergency delivery

Caesarean section · women in labour with signs of fetal distress and a fetal scalp pH < 7.25, for whom the decision had been made for emergency delivery

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings for selective ß2‐adrenergic agonist vs no tocolytic agent, whilst awaiting emergency delivery

Apgar score less than 7 at 5 minutes · women with fetal distress for whom the decision had been made to delivery by emergency caesarean section

Summary of findings for selective ß2‐adrenergic agonist showed no clear difference in 5‐minute Apgar score < 7 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs no tocolytic agent, whilst awaiting emergency delivery

Apgar score less than 7 at 5 minutes · women in labour with signs of fetal distress and a fetal scalp pH < 7.25, for whom the decision had been made for emergency delivery

Summary of findings for subcutaneous terbutaline showed no clear difference in 5‐minute Apgar score < 7 compared with no tocolytic agent, whilst awaiting emergency delivery (low certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs no tocolytic agent, whilst awaiting emergency delivery

Abnormal FHR tracing · women in labour with signs of fetal distress and a fetal scalp pH < 7.25, for whom the decision had been made for emergency delivery

Summary of findings for subcutaneous terbutaline probably leads to lower abnormal FHR tracing compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review

Summary of findings for subcutaneous terbutaline vs no tocolytic agent, whilst awaiting emergency delivery

No improvement in FHR · women in labour with signs of fetal distress and a fetal scalp pH < 7.25, for whom the decision had been made for emergency delivery

Summary of findings for subcutaneous terbutaline probably leads to lower no improvement in FHR compared with no tocolytic agent, whilst awaiting emergency delivery (moderate certainty).

1 finding from 1 review