Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

550 questions · 669 findings · 42 reviews

No studies found 162 · 24.2%GRADE not reported 272 · 40.7%Very low 110 · 16.4%Low 93 · 13.9%Moderate 29 · 4.3%High 3 · 0.4%

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Marginal deterioration of the restoration and fracture of the remaining tooth tissue · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Restoration survival · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Economic data: direct costs of materials and any reported associated indirect costs · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Signs of acute toxicity during gel application (nausea, gagging, vomiting) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

It is very uncertain whether fluoride mouthrinse (any fluoride agent, concentration, volume,… changes unacceptability of treatment as measured by leaving study early… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Adverse effects · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Post‐insertion sensitivity or pain assessed by a validated pain scale · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Tooth staining/discolouration (adverse effect) · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo or no treatment

Unacceptability of treatment (dropouts/exclusions during the trial) · Children and adolescents aged 16 years or less

Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in unacceptability of treatment (dropouts/exclusions during the trial) compared with placebo or no treatment; GRADE not reported.

3 findings from 1 review

Xylitol syrup (high dose, 8 g/day) vs Control (low-dose xylitol, 2.67 g/day) syrup

Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo or no treatment

Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review