Findings

What do systematic reviews say?

4,783 questions · 10,022 findings · 882 reviews

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No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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Any antihypertensive drug vs no antihypertensive drugs/placebo

Small‐for‐gestational age · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in small‐for‐gestational age compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.96 [0.78, 1.18]
21 studies · 2686 participants
Moderate

Any antihypertensive drug vs no antihypertensive drugs/placebo

Preterm birth · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in preterm birth (< 37 weeks) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.96 [0.83, 1.12]
15 studies · 2141 participants
Moderate

Any antihypertensive drug vs no antihypertensive drugs/placebo

Maternal death · women with mild to moderate hypertension during pregnancy

It is very uncertain whether any antihypertensive drug changes maternal death compared with no antihypertensive drugs/placebo (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 1.11 [0.18, 7.02]
5 studies · 525 participants
Very low