Alpha‐lipoic acid vs placebo
Change in any validated quality of life score · people with DPN
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
4,756 questions · 13,493 findings · 1,305 reviews · Headline outcomes only
No studies found 2,594 · 19.2%GRADE not reported 728 · 5.4%Very low 2,868 · 21.3%Low 3,777 · 28%Moderate 2,620 · 19.4%High 906 · 6.7%
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Alpha‐lipoic acid vs placebo
Complications of DPN · people with DPN
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Alpha‐lipoic acid vs placebo
Withdrawals due to adverse events · people with DPN
Alpha‐lipoic acid showed no clear difference in adverse events leading to cessation of treatment compared with placebo (moderate certainty).
1 finding from 1 review
- RR 1.48 [0.5, 4.35]3 studies · 1090 participantsModerate
Manual therapy, prescribed exercises or both vs placebo
Mean pain intensity (Numeric Rating Scale 0–10) · lateral elbow pain
1 finding from 1 review
- no estimate extracted1 study · 23 participantsLow
Manual therapy, prescribed exercises or both vs placebo
DisabilityScale: 0 to 100 (0 is no disability) · lateral elbow pain
1 finding from 1 review
- no estimate extracted1 study · 23 participantsLow
Manual therapy, prescribed exercises or both vs placebo
Quality of life · lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Manual therapy, prescribed exercises or both vs placebo
Global assessment of treatment success · lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Manual therapy, prescribed exercises or both vs placebo
Proportion of withdrawals · lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Manual therapy, prescribed exercises or both vs placebo
Proportion with adverse events · lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Manual therapy, prescribed exercises or both vs placebo
Proportion with a serious adverse event · lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Testosterone vs placebo
Erectile function · men with sexual dysfunction
3 findings from 1 review
- no estimate extracted3 studies · 792 participantsModerate
- no estimate extracted6 studies · 2016 participantsModerate
- no estimate extracted1 study · 42 participantsVery low
Testosterone vs placebo
Sexual quality of life · men with sexual dysfunction
The review found no eligible studies for this question.
3 findings from 1 review
- no estimate extractedStudies not reportedNo studies found
- no estimate extracted5 studies · 1030 participantsModerate
- no estimate extracted2 studies · 786 participantsModerate
Testosterone vs placebo
Cardiovascular mortality · men with sexual dysfunction
The review found no eligible studies for this question.
2 findings from 1 review
- no estimate extractedStudies not reportedNo studies found
- RR 0.83 [0.21, 3.26]10 studies · 3525 participantsModerate
Testosterone vs placebo
Withdrawals due to adverse events · men with sexual dysfunction
It is very uncertain whether testosterone changes treatment withdrawal due to adverse events compared with placebo (very low certainty).
2 findings from 1 review
- RR 1.04 [0.58, 1.86]2 studies · 122 participantsVery low
- RR 0.81 [0.56, 1.19]12 studies · 2966 participantsModerate
Testosterone vs placebo
Prostate‐related events · men with sexual dysfunction
The review found no eligible studies for this question.
2 findings from 1 review
- no estimate extractedStudies not reportedNo studies found
- RR 1.65 [1.08, 2.51]10 studies · 3439 participantsModerate
Testosterone vs placebo
Lower urinary tract symptoms · men with sexual dysfunction
The review found no eligible studies for this question.
2 findings from 1 review
- no estimate extractedStudies not reportedNo studies found
- no estimate extracted6 studies · 1488 participantsModerate
Intervention not reported
Total studies: 47 Total participants: 4398 · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review
- Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes onlyno estimate extracted47 participantsGRADE not reported
Intervention not reported
TXA given intra‐articularly at a total dose of 2 g intraoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review
- Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes onlyno estimate extracted2 participantsLow
Intervention not reported
TXA given intravenously at a total dose of 1 g intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review
- Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes onlyno estimate extracted1 participantsLow
Intervention not reported
TXA given orally at a total dose of greater than 3 g pre‐incision and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review
- Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a… 2024 · Cochrane Headline outcomes onlyno estimate extracted3 participantsVery low