Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

520 questions · 527 findings · 55 reviews · Headline outcomes only

No studies found 140 · 26.6%GRADE not reported 66 · 12.5%Very low 121 · 23%Low 115 · 21.8%Moderate 77 · 14.6%High 8 · 1.5%

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Intraventricular haemorrhage, Papile grade 3/4 · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes intraventricular haemorrhage grade III or IV compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Patent ductus arteriosus · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes patent ductus arteriosus compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Oxygen requirement at 36 weeks' postmenstrual age · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes chronic lung disease (oxygen supplementation at 36 weeks'… compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Proven necrotising enterocolitis (Bell's stage II or III) · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes proven necrotising enterocolitis (Bell's stage II or III) compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Retinopathy of prematurity, any or severe (stage ≥ III) · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes retinopathy of prematurity, any or severe (stage ≥ III) compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

All‐cause mortality · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation probably leads to lower all‐cause mortality compared with standard care (moderate certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

Major bleeding · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation showed no clear difference in major haemorrhage compared with standard care (low certainty).

1 finding from 1 review

self‐management of oral anticoagulation vs usual care

Minor haemorrhage · Patients on long‐term anticoagulant therapy (treatment duration longer than two months) irrespective of the indication for treatment

self‐management of oral anticoagulation showed no clear difference in minor haemorrhage compared with standard care (low certainty).

1 finding from 1 review