What do systematic reviews say?

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

It is very uncertain whether flutamide 250 mg once to twice daily changes proportion of participants who reported an adverse event compared with metformin 1275 mg to 1700 mg per day (very low certainty).

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  RR 2 [0.41, 9.71]
  1 study · 40 participants
  Very low

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 95 participants
  Very low

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 95 participants
  Moderate

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 95 participants
  Very low

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 55 participants
  Moderate

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 136 participants
  Moderate

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Moderate

Budesonide 6‐9 mg vs azathioprine (AZA)

It is very uncertain whether budesonide 6‐9 mg changes continued remission at 12 months compared with azathioprine 2‐2.5 mg/kg (very low certainty).

• Budesonide for maintenance of remission in Crohn's disease 2014 · Cochrane Headline outcomes only
  RR 0.81 [0.61, 1.08]
  1 study · 77 participants
  Very low

Loratadine 10 mg vs desloratadine 5 mg

Loratadine 10 mg showed no clear difference in complete suppression of urticaria: intermediate‐term duration of… compared with desloratadine 5 mg (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 0.91 [0.78, 1.06]
  2 studies · 369 participants
  Low

Loratadine 10 mg vs desloratadine 5 mg

Loratadine 10 mg showed no clear difference in good or excellent response: intermediate‐term duration of… compared with desloratadine 5 mg (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 1.04 [0.64, 1.71]
  3 studies · 410 participants
  Low

Loratadine 10 mg vs hydroxyzine 25 mg

Loratadine 10 mg showed no clear difference in complete suppression of urticaria: short‐term duration of… compared with hydroxyzine 25 mg (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 1 [0.32, 3.1]
  1 study · 12 participants
  Low

Cetirizine 10 mg/d vs hydroxyzine 25 mg

Cetirizine 10 mg showed no clear difference in adverse events leading to withdrawal compared with hydroxyzine 25 mg (low certainty).

• H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only
  RR 0.78 [0.25, 2.45]
  2 studies · 261 participants
  Low