What do systematic reviews say?

Unfractionated heparin vs no pharmacological anticoagulation

The review found no eligible studies for this question.

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Unfractionated heparin vs no pharmacological anticoagulation

The review found no eligible studies for this question.

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Unfractionated heparin vs no pharmacological anticoagulation

The review found no eligible studies for this question.

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Citrate vs unfractionated heparin

Citrate showed no clear difference in death at 28 days compared with unfractionated heparin (moderate certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 1.06 [0.86, 1.3]
  5 studies · 462 participants
  Moderate

Unfractionated heparin vs no pharmacological anticoagulation

The review found no eligible studies for this question.

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Unfractionated heparin vs no pharmacological anticoagulation

The review found no eligible studies for this question.

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Citrate vs unfractionated heparin

Citrate probably leads to higher successful prevention of clotting compared with unfractionated heparin (moderate certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 1.44 [1.1, 1.87]
  3 studies · 88 participants
  Moderate

Citrate vs unfractionated heparin

Citrate showed no clear difference in treatment cessation due to adverse events compared with unfractionated heparin (low certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 0.47 [0.15, 1.49]
  3 studies · 412 participants
  Low

Citrate vs unfractionated heparin

Citrate showed no clear difference in recovery of kidney function compared with unfractionated heparin (low certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 1.04 [0.89, 1.21]
  2 studies · 214 participants
  Low

Citrate vs unfractionated heparin

Citrate showed no clear difference in thrombocytopenia compared with unfractionated heparin (low certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 0.39 [0.14, 1.03]
  3 studies · 412 participants
  Low

Citrate vs unfractionated heparin

The review found no eligible studies for this question.

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Unfractionated heparin vs low molecular weight heparin

Unfractionated heparin showed no clear difference in major bleeding compared with low molecular weight heparin (low certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 0.58 [0.13, 2.58]
  5 studies · 153 participants
  Low

Unfractionated heparin vs low molecular weight heparin

It is very uncertain whether unfractionated heparin changes death: unknown time frame compared with low molecular weight heparin (very low certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 0.78 [0.51, 1.18]
  1 study · 29 participants
  Very low

Intervention vs control

• Interventions outside the workplace for reducing sedentary behaviour in adults under 60 years of age 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 participants
  GRADE not reported

Intervention vs control

• Interventions outside the workplace for reducing sedentary behaviour in adults under 60 years of age 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 participants
  GRADE not reported

Intervention vs control

• Interventions outside the workplace for reducing sedentary behaviour in adults under 60 years of age 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 participants
  GRADE not reported

Intervention vs control

• Interventions outside the workplace for reducing sedentary behaviour in adults under 60 years of age 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 participants
  GRADE not reported

Intervention vs control

The review found no eligible studies for this question.

• Interventions outside the workplace for reducing sedentary behaviour in adults under 60 years of age 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pulmonary rehabilitation vs no intervention

• Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD) 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 190 participants
  Low

Intervention not reported

• Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD) 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 411 participants
  Low