What do systematic reviews say?

CHRONIC: ACEi or ARB vs placebo

It is very uncertain whether CHRONIC: ACEi or ARB changes heart failure hospitalisation ( compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.9 [0.43, 1.9]
  2 studies · 1368 participants
  Very low

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

It is very uncertain whether CHRONIC: ACEi or ARB changes hypotension (ARB; withdrawn from study) compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 2.6 [1.12, 6.07]
  1 study · 332 participants
  Very low

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: ACEi or ARB vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: Beta‐blockers vs placebo

CHRONIC: Beta‐blockers probably leads to lower death (any cause) ( compared with placebo (moderate certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.69 [0.6, 0.79]
  4 studies · 3136 participants
  Moderate

ACUTE: Serelaxin vs placebo

ACUTE: Serelaxin showed no clear difference in cardiovascular death compared with placebo (low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.47 [0.21, 1.08]
  2 studies · 1395 participants
  Low

CHRONIC: Beta‐blockers vs placebo

CHRONIC: Beta‐blockers may leads to lower cardiovascular death ( compared with placebo (low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.53 [0.35, 0.81]
  3 studies · 2287 participants
  Low

CHRONIC: Beta‐blockers vs placebo

CHRONIC: Beta‐blockers showed no clear difference in hospitalisation (any cause) compared with placebo (low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.75 [0.52, 1.08]
  2 studies · 1583 participants
  Low

CHRONIC: Beta‐blockers vs placebo

CHRONIC: Beta‐blockers showed no clear difference in heart failure hospitalisation ( compared with placebo (low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.67 [0.43, 1.05]
  3 studies · 2287 participants
  Low

CHRONIC: Beta‐blockers vs placebo

It is very uncertain whether CHRONIC: Beta‐blockers changes worsening heart failure compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 1.36 [0.58, 3.2]
  1 study · 704 participants
  Very low

CHRONIC: Beta‐blockers vs placebo

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 704 participants
  Very low

CHRONIC: Beta‐blockers vs placebo

It is very uncertain whether CHRONIC: Beta‐blockers changes hypotension compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 5.11 [0.25, 106.15]
  1 study · 704 participants
  Very low

CHRONIC: Beta‐blockers vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CHRONIC: Beta‐blockers vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs placebo

It is very uncertain whether CHRONIC: Aldosterone antagonists changes death (any cause) ( compared with placebo (very low certainty).

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  RR 0.61 [0.06, 6.59]
  2 studies · 34 participants
  Very low

Aldosterone antagonists vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ACUTE: Serelaxin vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Aldosterone antagonists vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found