Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,736 questions · 15,265 findings · 1,163 reviews · Headline outcomes only

No studies found 3,871 · 25.4%GRADE not reported 810 · 5.3%Very low 4,242 · 27.8%Low 3,879 · 25.4%Moderate 1,999 · 13.1%High 464 · 3%

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Alarm vs miscellaneous treatments

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

It is very uncertain whether alarm changes proportion of children achieving 14 consecutive dry nights by the… compared with miscellaneous treatments (very low certainty).

4 findings from 1 review
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Alarm vs miscellaneous treatments

Proportion of children dry at · children with nocturnal enuresis

It is very uncertain whether alarm changes proportion of children dry at compared with miscellaneous treatments (very low certainty).

2 findings from 1 review

Alarm vs placebo drug

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

Alarm may leads to higher proportion of children achieving 14 consecutive dry nights by the… compared with placebo drug (low certainty).

1 finding from 1 review

Intervention not reported

Death at one year · adults with renal vasculitis

The intervention showed no clear difference in death at one year (low certainty).

1 finding from 1 review

Pulse cyclophosphamide vs continuous cyclophosphamide

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment] · adults with renal vasculitis

Pulse cyclophosphamide may leads to higher relapse at the end of compared with continuous cyclophosphamide (low certainty).

1 finding from 1 review