Findings

What do systematic reviews say?

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Sitagliptin vs glipizide

All cardiovascular death · people with diabetes and CKD

The review found no eligible studies for this question.

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sitagliptin vs glipizide

Weight (kg) · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 552 participants
Low

Sitagliptin vs glipizide

eGFR · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 552 participants
Low

Sitagliptin vs glipizide

Hypoglycaemia · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 551 participants
Moderate

SGLT2 inhibitors vs placebo

All cardiovascular death · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2788 participants
Low

Sitagliptin vs glipizide

Discontinuation of medication due to adverse events · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 551 participants
Very low

SGLT2 inhibitors vs placebo

Weight (kg) · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1029 participants
Low

SGLT2 inhibitors vs placebo

eGFR · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 848 participants
Moderate

SGLT2 inhibitors vs placebo

Hypoglycaemia · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 3086 participants
Low

SGLT2 inhibitors vs placebo

Discontinuation of medication due to adverse events · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 917 participants
Very low

DPP‐4 inhibitors vs placebo

HbA1c (%) · people with diabetes and CKD

1 finding from 1 review

Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 867 participants
Low

Psychological therapy vs control

Severity of PTSD symptoms · adults (aged 18 and older) exposed to a traumatic event

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 1272 participants
Low

Psychological therapy vs control

Somatic symptoms and related disorders · children exposed to traumatic events

The review found no eligible studies for this question.

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological therapy vs control

Depression at endpoint · adults (aged 18 and older) exposed to a traumatic event

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 1254 participants
Low

Psychological therapy vs control

Anxiety · adults (aged 18 and older) exposed to a traumatic event

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 694 participants
Low

Psychological therapy vs control

Leaving the study early · adults (aged 18 and older) exposed to a traumatic event

Psychological therapy showed no clear difference in dropouts for any reason compared with control (moderate certainty).

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
RR 0.98 [0.82, 1.16]
23 studies · 2950 participants
Moderate

Psychological therapy vs control

Somatic symptoms and related disorders · adults (aged 18 and older) exposed to a traumatic event

The review found no eligible studies for this question.

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological therapy vs control

Severity of PTSD symptoms · children exposed to traumatic events

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 130 participants
Very low

Psychological therapy vs control

Depression at endpoint · children exposed to traumatic events

The review found no eligible studies for this question.

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological therapy vs control

Anxiety · children exposed to traumatic events

The review found no eligible studies for this question.

1 finding from 1 review

Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found