Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,720 questions · 15,377 findings · 900 reviews

No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Alarm plus other intervention vs other interventions

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

It is very uncertain whether alarm plus other intervention changes proportion of children achieving 14 consecutive dry nights by the… compared with other intervention (very low certainty).

3 findings from 1 review

Alarm plus other intervention vs other interventions

Proportion of children dry at · children with nocturnal enuresis

Alarm plus other intervention showed no clear difference in proportion of children dry at compared with other intervention (low certainty).

2 findings from 1 review

Alarm vs placebo drug

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

Alarm may leads to higher proportion of children achieving 14 consecutive dry nights by the… compared with placebo drug (low certainty).

1 finding from 1 review

Intervention not reported

Death at one year · adults with renal vasculitis

The intervention showed no clear difference in death at one year (low certainty).

1 finding from 1 review

Pulse cyclophosphamide vs continuous cyclophosphamide

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment] · adults with renal vasculitis

Pulse cyclophosphamide may leads to higher relapse at the end of compared with continuous cyclophosphamide (low certainty).

1 finding from 1 review