Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Dual therapy (angiotensin‐converting‐enzyme inhibitors plus angiotensin receptor blockers) vs placebo or no treatment

Fatal or nonfatal myocardial infarction · people with diabetes and kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Dual therapy (angiotensin‐converting‐enzyme inhibitors plus angiotensin receptor blockers) vs placebo or no treatment

Micro‐ to normoalbuminuria6 · people with diabetes and kidney disease

It is very uncertain whether dual therapy (angiotensin‐converting‐enzyme inhibitors plus… changes micro‐ to normoalbuminuria6 compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Death or serious morbidity composite · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in composite of mortality or serious morbidity (as defined by trial) compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (low certainty).

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Neurosensory disability · Children (as neonate, child, adult) of women with GDM

The review found no eligible studies for this question.

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Infant hypoglycaemia · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in infant hypoglycaemia compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (moderate certainty).

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Diabetes · Children (as neonate, child, adult) of women with GDM

The review found no eligible studies for this question.

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Induction of labour · women with gestational diabetes mellitus

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in induction of labour compared with less‐tight glycaemic targets (maternal outcomes) (moderate certainty).

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Large‐for‐gestational age · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in large‐for‐gestational‐age compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (moderate certainty).

1 finding from 1 review