Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,005 questions · 1,053 findings · 151 reviews · Headline outcomes only

No studies found 275 · 26.1%GRADE not reported 150 · 14.2%Very low 271 · 25.7%Low 215 · 20.4%Moderate 105 · 10%High 37 · 3.5%

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Leaving the study early · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in leaving the study early: For any reason compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review

COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) vs TAU

Leaving the study early · Adolescents with psychosis

It is very uncertain whether COGNITIVE REMEDIATION THERAPY (CRG) + TREATMENT‐AS‐USUAL (TAU) changes leaving the study early: For any reason compared with TAU (all short‐term) (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Side effects (any reported throughout the intervention period) (ALL) · treating leg cramps in pregnancy

Oral magnesium showed no clear difference in side effects ‐ any compared with placebo/no treatment (low certainty).

1 finding from 1 review

Intervention not reported

Transepidermal water loss (TEWL) Measured using temperature‐adjusted g/m²/h with the Tewameter TM 300 (Courage + Khazaka, Cologne, Germany) Hahnel 2017: measured at 56 ± 4 days Shishido 2017: measured 15 minutes after wiping the skin with a dry to... · people 60 years of age and older
1 finding from 1 review

Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo

Development of any new foot ulcers · people with diabetes and foot ulcers

It is very uncertain whether arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement changes development of any new foot ulcers compared with placebo (very low certainty).

1 finding from 1 review