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What do systematic reviews say?

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Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

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No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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Intervention not reported

Function Lequesne algofunctional index 0‐24 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Radiographic joint changes · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with treating osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Persea gratissma + Glycine max (ASU 300 mg) vs chondroitin sulphate

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis

Persea gratissma + Glycine max (ASU 300 mg) showed no clear difference in adverse events Participants (n) reported serious adverse events compared with chondroitin sulphate (low certainty).

1 finding from 1 review

Intervention not reported

Radiographic joint changes · patients with treating osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life · patients with treating osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain Global pain VAS 0‐100 (higher scores mean worse) · patients with treating osteoarthritis
1 finding from 1 review

Intervention not reported

Function WOMAC‐VAS (Function) · patients with treating osteoarthritis
1 finding from 1 review

Intervention not reported

At least 50% of maximum pain relief over 4 to 6 hours · adults with moderate or severe acute postoperative pain

The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 hours (high certainty).

1 finding from 1 review

Intervention not reported

Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain

The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).

1 finding from 1 review