Minor adverse events · participants with acne
Nicotinamide showed no clear difference in total number of participants who experienced at least one minor… compared with clindamycin (low certainty).
1 finding from 1 review
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · participants with acne
Nicotinamide showed no clear difference in withdrawal for any reason (medium term: treatment duration from 5 to… compared with erythromycin (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement Fair to good improvement (long term: treatment duration > 8 weeks) · participants with acne
Glycolic acid (alpha‐hydroxy acid) showed no clear difference in participants' global self‐assessment of acne improvement Fair to… compared with salicylic‐mandelic acid (low certainty).
1 finding from 1 review
Treatment withdrawal · participants with acne
1 finding from 1 review
Minor adverse events · participants with acne
It is very uncertain whether glycolic acid (alpha‐hydroxy acid) changes total number of participants who experienced at least one minor… compared with salicylic‐mandelic acid (very low certainty).
1 finding from 1 review
Secondary outcome: Dermatology Quality of Life measure · participants with acne
1 finding from 1 review
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne
Azelaic acid probably leads to lower participants' global self‐assessment of acne improvement Good or… compared with benzoyl peroxide (moderate certainty).
1 finding from 1 review
Treatment withdrawal · participants with acne
Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with benzoyl peroxide (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
It is very uncertain whether azelaic acid changes total number of participants who experienced at least one minor… compared with benzoyl peroxide (very low certainty).
1 finding from 1 review
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne
Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good or… compared with clindamycin (low certainty).
1 finding from 1 review
Intervention not reported
Frequency of skin damage (as recorded by clinicians according to STAR Skin Tear Classification) Outcome measured during 6 months · people 60 years of age and older
1 finding from 1 review
Intervention not reported
Side effects from intervention (as and when observed) Outcome measured up to day 56 ± 4 · people 60 years of age and older
1 finding from 1 review
Intervention not reported
Transepidermal water loss (TEWL) Measured using temperature‐adjusted g/m²/h with the Tewameter TM 300 (Courage + Khazaka, Cologne, Germany) Hahnel 2017: measured at 56 ± 4 days Shishido 2017: measured 15 minutes after wiping the skin with a dry to... · people 60 years of age and older
1 finding from 1 review
Intervention not reported
Stratum corneum hydration (SCH) (at baseline and day 56 ± 4) Hahnel 2017: measured at 56 ± 4 days in mid‐volar arm and lower leg in arbitrary units from 0 (no water) to 120 (on water) using the Corneometer CM 825 Gillis 2016: measured at 12 weeks ... · people 60 years of age and older
1 finding from 1 review