Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

472 questions · 481 findings · 37 reviews

No studies found 118 · 24.5%GRADE not reported 41 · 8.5%Very low 176 · 36.6%Low 99 · 20.6%Moderate 34 · 7.1%High 13 · 2.7%

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: j. ZUCLOPENTHIXOL ACETATE

Tremor · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: specific ‐ tremor by 7 days compared with OTHER ANTIPSYCHOTIC: k. ZUCLOPENTHIXOL ACETATE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs BENZODIAZEPINE: a. FLUNITRAZEPAM

Specific behaviours ‐ Aggression 50% reduction in OAS score at 90 minutes · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes specific behaviours ‐ aggression 50% reduction in OAS score at 90… compared with BENZODIAZEPINE: a. FLUNITRAZEPAM (very low certainty).

1 finding from 1 review

HALOPERIDOL vs lorazepam

Global outcome: no overall improvement ‐ at 30 minutes · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome: no overall improvement ‐ at 60 minutes compared with BENZODIAZEPINE: b. LORAZEPAM (very low certainty).

1 finding from 1 review

HALOPERIDOL vs lorazepam

Adverse effects: specific ‐ dystonia · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: specific ‐ dystonia (only reported if occurred in… compared with BENZODIAZEPINE: b. LORAZEPAM (very low certainty).

1 finding from 1 review

HALOPERIDOL vs lorazepam

Adverse effects: Specific ‐ hypertonia/rigidity (only reported if occurred in ≥9%) during 24 hours · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: specific ‐ hypertonia/rigidity (only reported if… compared with BENZODIAZEPINE: b. LORAZEPAM (very low certainty).

1 finding from 1 review