a) Cerebral palsy or gross motor disability · preterm infants prior to extubation
Methylxanthine probably leads to lower a) Cerebral palsy or gross motor disability compared with placebo or control (moderate certainty).
1 finding from 1 review
b) Developmental delay at 18 to 24 months · preterm infants prior to extubation
Methylxanthine showed no clear difference in b) Developmental delay at 18 to 24 months compared with placebo or control (moderate certainty).
1 finding from 1 review
Failed extubation · preterm infants prior to extubation
Methylxanthine probably leads to lower failed extubation compared with placebo or control (moderate certainty).
1 finding from 1 review
Oxygen requirement at 36 weeks' postmenstrual age · preterm infants prior to extubation
Methylxanthine probably leads to lower supplemental oxygen at 36 weeks' postmenstrual age compared with placebo or control (moderate certainty).
1 finding from 1 review
a) Cerebral palsy or gross motor disability · preterm infants at risk of or with apnea; preterm infants undergoing extubation
Methylxanthine probably leads to lower a) Cerebral palsy or gross motor disability compared with placebo or control (moderate certainty).
1 finding from 1 review
b) Developmental delay at 18 to 24 months · preterm infants at risk of or with apnea; preterm infants undergoing extubation
Methylxanthine showed no clear difference in b) Developmental delay at 18 to 24 months compared with placebo or control (moderate certainty).
1 finding from 1 review
Any apneic episodes · preterm infants at risk of or with apnea; preterm infants undergoing extubation
Methylxanthine probably leads to lower any apneic episodes compared with placebo or control (moderate certainty).
1 finding from 1 review
Failed apnea reduction · preterm infants at risk of or with apnea; preterm infants undergoing extubation
Methylxanthine probably leads to lower failed apnea reduction compared with placebo or control (moderate certainty).
1 finding from 1 review
Positive‐pressure ventilation after institution of treatment · preterm infants at risk of or with apnea; preterm infants undergoing extubation
Methylxanthine may leads to lower positive‐pressure ventilation after institution of treatment compared with placebo or control (low certainty).
1 finding from 1 review
Oxygen requirement at 36 weeks' postmenstrual age · preterm infants at risk of or with apnea; preterm infants undergoing extubation
Methylxanthine leads to lower supplemental oxygen at 36 weeks' postmenstrual age compared with placebo or control (high certainty).
1 finding from 1 review
Caesarean section · women with gestational diabetes mellitus and their babies
Fetal biometry showed no clear difference in caesarean delivery compared with maternal glycaemic values (low certainty).
1 finding from 1 review
Maternal Hypoglycaemia ‐ not reported · women with gestational diabetes mellitus and their babies
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hypertensive disorders of pregnancy · women with gestational diabetes mellitus and their babies
It is very uncertain whether fetal biometry changes hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with maternal glycaemic values (very low certainty).
1 finding from 1 review
Development of T2DM in mother ‐ not reported · women with gestational diabetes mellitus and their babies
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Large‐for‐gestational age · women with gestational diabetes mellitus and their babies
It is very uncertain whether fetal biometry changes large‐for‐gestational age compared with maternal glycaemic values (very low certainty).
1 finding from 1 review
Shoulder dystocia · women with gestational diabetes mellitus and their babies
It is very uncertain whether fetal biometry changes shoulder dystocia compared with maternal glycaemic values (very low certainty).
1 finding from 1 review
Health status and well‐being – neonatal morbidity and mortality combined · women with gestational diabetes mellitus and their babies
It is very uncertain whether fetal biometry changes composite outcome neonatal morbidity or mortality compared with maternal glycaemic values (very low certainty).
1 finding from 1 review
Neonatal hypoglycaemia · women with gestational diabetes mellitus and their babies
Fetal biometry showed no clear difference in neonatal hypoglycaemia compared with maternal glycaemic values (low certainty).
1 finding from 1 review
Perinatal mortality · women with gestational diabetes mellitus and their babies
It is very uncertain whether fetal biometry changes perinatal mortality compared with maternal glycaemic values (very low certainty).
1 finding from 1 review
Disease control (time when steroid could be discontinued) · bullous pemphigoid
1 finding from 1 review