Intervention not reported
4a. Procedural crying (during and immediately after the vaccination procedure) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP combination vaccine
1 finding from 1 review
Intervention not reported
4b. Persistent inconsolable crying8 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP combination vaccine
It is very uncertain whether the intervention changes 4b. Persistent inconsolable crying8 (very low certainty).
1 finding from 1 review
Intervention not reported
2a. Adequate immune response (seroprotection) against diphtheria (surrogate outcome) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention showed no clear difference in 2a. Adequate immune response (seroprotection) against diphtheria… (moderate certainty).
1 finding from 1 review
Intervention not reported
Severe local reaction11 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP combination vaccine
1 finding from 1 review
Intervention not reported
Non‐severe local reaction13 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP combination vaccine
The intervention showed no clear difference in non‐severe local reaction13 (low certainty).
1 finding from 1 review
Intervention not reported
Fever · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP combination vaccine
1 finding from 1 review
Intervention not reported
Incidence of diphtheria, tetanus, pertussis, Haemophilus influenzae type b (Hib) (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
2a. Adequate immune response (seroprotection) against diphtheria (surrogate outcome) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention showed no clear difference in 2a. Adequate immune response (seroprotection) against diphtheria… (moderate certainty).
1 finding from 1 review
Intervention not reported
2b. Adequate immune response (seroprotection) against tetanus (surrogate outcome) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention showed no clear difference in 2b. Adequate immune response (seroprotection) against tetanus… (moderate certainty).
1 finding from 1 review
Intervention not reported
2c. Adequate immune response (seroprotection) against pertussis (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
2d. Adequate immune response (seroprotection) against Haemophilus influenzae type b disease (surrogate outcome) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention showed no clear difference in 2d. Adequate immune response (seroprotection) against Haemophilus… (moderate certainty).
1 finding from 1 review
Intervention not reported
Pain (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
4a. Procedural crying (during and immediately after the vaccination procedure) (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
2b. Adequate immune response (seroprotection) against tetanus (surrogate outcome) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention showed no clear difference in 2b. Adequate immune response (seroprotection) against tetanus… (moderate certainty).
1 finding from 1 review
Intervention not reported
4b. Persistent inconsolable crying4 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
It is very uncertain whether the intervention changes 4b. Persistent inconsolable crying4 (very low certainty).
1 finding from 1 review
Intervention not reported
Severe local reaction8 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention probably leads to lower severe local reaction8 (moderate certainty).
1 finding from 1 review
Intervention not reported
Non‐severe local reaction11 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention probably leads to lower non‐severe local reaction11 (moderate certainty).
1 finding from 1 review
Intervention not reported
Fever15 · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
It is very uncertain whether the intervention changes fever15 (very low certainty).
1 finding from 1 review
Intervention not reported
2c. Adequate immune response (seroprotection) against pertussis (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
2d. Adequate immune response (seroprotection) against Haemophilus influenzae type b disease (surrogate outcome) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine
The intervention probably leads to higher 2d. Adequate immune response (seroprotection) against Haemophilus… (moderate certainty).
1 finding from 1 review