Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,361 questions · 1,518 findings · 352 reviews

No studies found 73 · 4.8%GRADE not reported 211 · 13.9%Very low 500 · 32.9%Low 411 · 27.1%Moderate 252 · 16.6%High 71 · 4.7%

Summary of findings table ‐ Platinum‐resistant recurrent EOC: PARPi monotherapy vs chemotherapy alone

Adverse events (grade ≥ 3) · recurrent platinum‐resistant EOC

It is very uncertain whether summary of findings table ‐ Platinum‐resistant recurrent EOC: PARPi… changes any severe adverse events (grade 3 or higher) (G3+ SevAE) compared with chemotherapy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi with chemotherapy vs chemotherapy alone

Adverse events (grade ≥ 3) · newly‐diagnosed EOC

Summary of findings table ‐ Newly‐diagnosed EOC: PARPi with… leads to higher any severe adverse event (grade 3 or higher) (G3+ SevAE) compared with chemotherapy alone (high certainty).

1 finding from 1 review

Mobility training vs control: subgroups with or without cognitive impairments

Level of functioning · older people living in the community with frailty
2 findings from 1 review

Mobility training vs control: subgroups with or without cognitive impairments

Mobility · older people living in the community with frailty
2 findings from 1 review

Laser therapy vs no treatment

Scar severity ‐ 585‐nm Pulsed‐Dye Laser (PDL) versus no treatment ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

Laser therapy may leads to higher scar severity ‐ 585‐nm Pulsed‐Dye Laser (PDL) versus no treatment ‐… compared with no treatment (low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Scar severity ‐ 585‐nm Pulsed‐Dye Laser (PDL) versus Triamcinolone acetonide (TAC) ‐ Vancouver Burn Scar (VBS) (Higher score = worse scar appearance) ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars
2 findings from 1 review