Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

534 questions · 539 findings · 63 reviews · Pregnancy and Childbirth

No studies found 101 · 18.7%GRADE not reported 63 · 11.7%Very low 93 · 17.3%Low 167 · 31%Moderate 89 · 16.5%High 26 · 4.8%

Bishop score vs transvaginal ultrasound

Neonatal admission to NICU · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in neonatal admission to NICU compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Need of misoprostol for cervical ripening · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score probably leads to lower need of misoprostol for cervical ripening compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Meconium staining of amniotic fluid · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in meconium staining of amniotic fluid compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Apgar score less than 7 at 5 minutes · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in apgar score at 5 minutes less than 7 compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or cerebral palsy (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Major neurodevelopmental disability at childhood · women at risk of preterm birth (< 34 weeks' gestation)

It is very uncertain whether magnesium sulphate changes major neurodevelopmental disability (school age)** compared with placebo (outcomes (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or major neurodevelopmental disability · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or major neurodevelopmental disability (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Severe maternal outcome potentially related to treatment (death, respiratory arrest, or cardiac arrest)** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in severe maternal outcome potentially related to treatment (death,… compared with placebo (outcomes (low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate leads to lower cerebral palsy (up to 2 years' corrected age)** compared with placebo (outcomes (high certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Major disability by 18 to 24 months corrected age (aligned definition) · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in major neurodevelopmental disability (up to 2 years' corrected age)** compared with placebo (outcomes (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Intraventricular haemorrhage, Papile grade 3/4 · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate probably leads to lower severe intraventricular haemorrhage (grade 3 or 4) (newborn/infant)** compared with placebo (outcomes (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Bronchopulmonary dysplasia/chronic lung disease · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in chronic lung disease/bronchopulmonary dysplasia (newborn/infant)** compared with placebo (outcomes (low certainty).

1 finding from 1 review

Intervention not reported

Caesarean section (all indications) Â · women with an abnormal CTG in labour

It is very uncertain whether the intervention changes caesarean section (all indications) Â (very low certainty).

1 finding from 1 review