Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,256 questions · 2,339 findings · 262 reviews

No studies found 555 · 23.7%GRADE not reported 398 · 17%Very low 572 · 24.5%Low 476 · 20.4%Moderate 240 · 10.3%High 98 · 4.2%

Mucoadhesive disk (carbomer/triglycerides + antimicrobial agents) vs Placebo disk

Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
  • Kerr 2010 (crossover, high risk of bias): no difference in oral dryness between active and placebo disks; increase in subjective oral moistness with both, persisting up to 2 weeks after last use (likely carryover);…
    1 study
    GRADE not reported

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Conditioning and sealing with an adhesive resin (smear-removing bonding system) vs Conventional calcium hydroxide lining

Maintenance of pulp vitality (freedom from pulpal breakdown) up to 36 months · Healthy adults with asymptomatic posterior permanent teeth with deep caries and a vital (non-exposed) pulp requiring restoration
1 finding from 1 review
  • Whitworth 2005: 602 teeth randomised; 39 emergency recalls over the 36 months after restoration, with pulp breakdown associated with 16 teeth. The authors concluded that "dentists should be confident that pulps will be…
    1 study · 602 participants
    GRADE not reported

Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast

Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring

The review found no eligible studies for this question.

2 findings from 1 review

Fixed prostheses cemented to prepared teeth after extraction or decoronation of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Self‐directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs usual care

Treatment success as defined by the authors · people with Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Self‐directed stress management (it is unclear whether these interventions replaced standard treatment or were added to standard treatment) vs usual care

Pain frequency or change in pain frequency · people with Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review