Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,734 questions · 15,288 findings · 893 reviews

No studies found 3,864 · 25.3%GRADE not reported 2,222 · 14.5%Very low 3,868 · 25.3%Low 3,280 · 21.5%Moderate 1,676 · 11%High 378 · 2.5%

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Active stimulation vs Placebo (sham/placebo device)

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic pain
3 findings from 1 review

Active stimulation vs Placebo (sham/placebo device)

Adverse event: lead failure/ displacement · adults with chronic pain

The review found no eligible studies for this question.

2 findings from 1 review

Active stimulation vs Placebo (sham/placebo device)

Adverse events: need for reoperation/ reimplantation · adults with chronic pain

The review found no eligible studies for this question.

3 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic pain
3 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Participant‐reported pain relief of 50% or greater · adults with chronic pain

It is very uncertain whether active stimulation + other intervention changes pain intensity. Proportion with ≥ 50% pain relief. compared with other intervention alone (very low certainty).

1 finding from 1 review

Active stimulation + other intervention vs other intervention alone

Adverse event: lead failure/ displacement · adults with chronic pain

The review found no eligible studies for this question.

3 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Adverse events: need for reoperation/ reimplantation · adults with chronic pain

The review found no eligible studies for this question.

2 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Pain intensity (number of people with ≥ 50% improvement) · adults with chronic pain

Active stimulation + other intervention may leads to higher pain intensity. Proportion with ≥50% pain relief. compared with other intervention alone (low certainty).

2 findings from 1 review

Active stimulation vs Placebo (sham/placebo device)

Adverse events: infection · adults with chronic pain

The review found no eligible studies for this question.

2 findings from 1 review