Findings

What do systematic reviews say?

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

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No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Intervention not reported

Fever clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 716 participants
Low

Intervention not reported

Death · adults with severe malaria

The intervention probably leads to higher death (moderate certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 1.8 [1.09, 2.97]
2 studies · 494 participants
Moderate

Intervention not reported

Coma resolution time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 494 participants
Moderate

Intervention not reported

Neurological sequelae at discharge · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Parasite clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 494 participants
Moderate

Intervention not reported

Fever clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 494 participants
Moderate

Intervention not reported

Coma resolution time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 358 participants
Low

Intervention not reported

Neurological sequelae at discharge · children with severe malaria

The intervention showed no clear difference in neurological sequelae at discharge (low certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.84 [0.66, 1.07]
7 studies · 968 participants
Low

Intervention not reported

Parasite clearance time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 420 participants
Moderate

Intervention not reported

Fever clearance time · children with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 457 participants
Low

Intervention not reported

Death · adults with severe malaria

The intervention probably leads to lower death (moderate certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 0.59 [0.42, 0.83]
4 studies · 716 participants
Moderate

Intervention not reported

Coma resolution time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 657 participants
Low

Intervention not reported

Neurological sequelae at discharge · adults with severe malaria

The intervention showed no clear difference in neurological sequelae at discharge (low certainty).

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
RR 2.92 [0.31, 27.86]
1 study · 560 participants
Low

Intervention not reported

Parasite clearance time · adults with severe malaria

1 finding from 1 review

Artemether for severe malaria 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 716 participants
Moderate

Effects of school‐based asthma interventions vs usual care

Exacerbation: hospital 17 weeks · children with asthma

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1873 participants
Moderate

Effects of school‐based asthma interventions vs usual care

Asthma symptoms leading to emergency hospital visits (ED visits) · children with asthma

Effects of school‐based asthma interventions may leads to lower asthma symptoms leading to emergency hospital visits (ED visits) compared with usual care (low certainty).

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
OR 0.7 [0.53, 0.92]
13 studies · 3883 participants
Low

Effects of school‐based asthma interventions vs usual care

Unplanned visit to hospital or GP due to asthma symptoms (unplanned medical visits) · children with asthma

Effects of school‐based asthma interventions probably leads to lower unplanned visit to hospital or GP due to asthma symptoms (unplanned… compared with usual care (moderate certainty).

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
OR 0.74 [0.6, 0.9]
5 studies · 3283 participants
Moderate

Effects of school‐based asthma interventions vs usual care

Absence from school · children with asthma

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 4609 participants
Low

Effects of school‐based asthma interventions vs usual care

Experience of daytime and night‐time symptoms ‐ daytime symptoms (daytime symptoms) · children with asthma

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1065 participants
Moderate

Effects of school‐based asthma interventions vs usual care

Use of reliever therapies, e.g. beta₂‐agonists (reliever therapies) · children with asthma

It is very uncertain whether effects of school‐based asthma interventions changes use of reliever therapies, e.g. beta₂‐agonists (reliever therapies) compared with usual care (very low certainty).

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
OR 0.52 [0.15, 1.81]
2 studies · 437 participants
Very low