Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,783 questions · 10,022 findings · 882 reviews

No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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Clindamycin plus aminoglycoside vs regimens containing quinolone

Clinical cure according to criteria established by study authors Severe PID · women with PID

Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors Severe PID compared with regimens containing quinolone (low certainty).

1 finding from 1 review

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Clinical cure according to criteria established by study authors Severe PID · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (low certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID

Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors… compared with regimens containing cephalosporin (low certainty).

1 finding from 1 review

Clindamycin plus aminoglycoside vs regimens containing cephalosporin

Clinical cure according to criteria established by study authors Severe PID · women with PID

Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors Severe PID compared with regimens containing cephalosporin (moderate certainty).

1 finding from 1 review

Regimens containing quinolone vs regimens containing cephalosporin

Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID

Regimens containing quinolone showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing cephalosporins (low certainty).

1 finding from 1 review

Rufinamide vs placebo

50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy

Rufinamide probably leads to higher 50% or greater reduction in seizure frequency ‐ ITT analysis compared with placebo (moderate certainty).

1 finding from 1 review