Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Intervention not reported

RT vs supportive care only · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention probably leads to lower RT vs supportive care only (moderate certainty).

1 finding from 1 review

Intervention not reported

Hypofractionated RT vs standard RT (60Gy/30 fractions) · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention led to lower hypofractionated RT vs standard RT (60Gy/30 fractions); GRADE not reported.

1 finding from 1 review

Intervention not reported

BEV_RT (1 RCT; 75 participants) · elderly people with newly diagnosed glioblastoma Interventions: radiotherapy with 40 Gy in 15 fractions (RT40); radiotherapy with 60 Gy in…

The intervention showed no clear difference in BEV_RT (1 RCT; 75 participants); GRADE not reported.

1 finding from 1 review

Intervention not reported

TMZ vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention showed no clear difference in TMZ vs RT (low certainty).

1 finding from 1 review

Intervention not reported

CRT vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention leads to lower CRT vs RT (high certainty).

1 finding from 1 review

Intervention not reported

BEV_CRT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention showed no clear difference in BEV_CRT vs CRT (low certainty).

1 finding from 1 review

Intervention not reported

BEV_RT vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention probably leads to lower BEV_RT vs RT (moderate certainty).

1 finding from 1 review

Intervention not reported

RIN_CRT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

TTF_AC vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

IRI_BEV_RT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

RT40 (4 RCTs; 930 participants) · elderly people with newly diagnosed glioblastoma Interventions: radiotherapy with 40 Gy in 15 fractions (RT40); radiotherapy with 60 Gy in…

The intervention may leads to lower RT40 (4 RCTs; 930 participants) (low certainty).

1 finding from 1 review