Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Two lag screws vs One lag screw (with arch bars and IMF)

Restoration of function (occlusion) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Restoration of the original occlusion, assessed visually, was similar in both groups (P>0.05); occlusal correction was not achieved in one participant in the two-lag-screws group. Surrogate/proxy outcome.
    1 study
    GRADE not reported

3-dimensional (3D) miniplates vs Standard (Champy) plates

Requirement for additional (surgical) interventions (post-operative MMF/IMF) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

3-dimensional (3D) miniplates led to lower requirement for additional (surgical) interventions (post-operative… compared with standard (Champy) plates; GRADE not reported.

1 finding from 1 review

Open (surgical) reduction and fixation vs Closed (non-surgical) treatment

Outcome not reported · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

The review found no eligible studies for this question.

1 finding from 1 review
  • "There were no studies comparing different types of closed interventions with one another or comparing open and closed interventions." "We found no studies that compared surgical with non-surgical treatments."
    0 studies
    No studies found

2 mm titanium plates vs 2.5 mm bioresorbable plates

Restoration of function (inability to chew hard food) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in restoration of function (inability to chew hard food) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Post-operative adverse events and complications (paraesthesia, swelling, segmental mobility) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Agarwal 2011: paraesthesia in one participant in the non-locking plate group (resolved by 3 months), none in the locking group; infection rates similar at 6 weeks and 3 months; post-operative swelling in 20% of both…
    1 study
    GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative neurosensory disturbance (mental nerve paraesthesia) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates led to higher post-operative neurosensory disturbance (mental nerve paraesthesia) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

2 mm titanium plates vs 2.5 mm bioresorbable plates

Requirement for additional (surgical) interventions (plate removal / re-operation) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Plate removal was statistically more likely in the titanium group (Fisher's exact P<0.05); infection led to plate removal in one titanium participant at 2 months and a further 4/21 (19%) titanium participants (six…
    1 study
    GRADE not reported

Locking plate vs 2 mm non-locking titanium plates

Requirement for additional (surgical) interventions · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Only Collins 2004 provided data: 6/122 participants had minor complications (three in each group); five required surgical removal of the locking plates and one post-operative malocclusion was managed with elastic…
    1 study · 122 participants
    GRADE not reported

Two lag screws vs One lag screw (with arch bars and IMF)

Post-operative adverse events and complications · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Three participants in the two-lag-screws group experienced complications: malocclusion (one) and mental-nerve paraesthesia (two, resolved after 3 months). There were no post-operative complications in the one-lag-screw…
    1 study
    GRADE not reported

3-dimensional (3D) miniplates vs Standard (Champy) plates

Post-operative adverse events and complications · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Jain 2010 (3D group): segmental mobility (two), proximity to mental nerve or roots (two), radiologically unsatisfactory reduction (one) and unsatisfactory fixation (four) vs one (standard); only fixation differed…
    2 studies
    GRADE not reported