What do systematic reviews say?

407 questions · 418 findings · 14 reviews · Endodontics and dental trauma

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No studies found 104 · 24.9%GRADE not reported 201 · 48.1%Very low 61 · 14.6%Low 41 · 9.8%Moderate 11 · 2.6%High 0 · 0%

Potassium nitrate/dimethyl isosorbide/polycarboxylate cement (KNO3/DMI/PCa) vs Polycarboxylate cement (PCa) alone

Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures

1 finding from 1 review

Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes
24 months
Hodosh 2003 (Analysis 3.1): all 18 patients receiving KNO3/DMI/PCa responded favourably (0/18 developed clinical symptoms) versus 10/12 in the PCa group. "The results in groups two and three were statistically…
1 study · 30 participants
GRADE not reported

Glycerrhetinic acid/antibiotic mixture vs Zinc oxide and eugenol (ZOE)

Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures

1 finding from 1 review

Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes
24 months
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
1 study · 275 participants
GRADE not reported

Post and core restoration with a ferrule vs Post and core restoration without a ferrule

Outcome not reported · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the final restoration

The review found no eligible studies for this question.

1 finding from 1 review

Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes
Minimum 6 months (planned)
No included trial evaluated the presence of a ferrule (a planned secondary comparison); no eligible study identified.
0 studies
No studies found

Non-metal carbon-fibre post and core (Category III; Composipost) vs Metal custom-cast post and core (Category I)

Clinical/technical failure (root fracture) · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the final restoration

Non-metal carbon-fibre post and core (Category III; Composipost) led to lower clinical/technical failure (root fracture) compared with metal custom-cast post and core (Category I; gold alloy); GRADE not reported.

1 finding from 1 review

Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes
48 months (4 years)
RR 0.05 [0.00, 0.90]
1 study · 195 participants
GRADE not reported

Potassium nitrate/polycarboxylate cement (KNO3/PCa) vs Polycarboxylate cement (PCa) alone

Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures

1 finding from 1 review

Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes
24 months
Hodosh 2003 (Analysis 3.1): 9/17 in the KNO3/PCa group and 10/12 in the PCa group developed clinical symptoms requiring endodontic therapy or extraction. No significance test reported for this specific contrast; no…
1 study · 29 participants
GRADE not reported

Direct composite resin restoration vs Full-coverage metal-ceramic crown

Clinical failure (post dislodgement) · Participants with endodontically-treated permanent premolars restored with a carbon-fibre post (Category III)

Direct composite restoration (final restoration) showed no clear difference in clinical failure (post dislodgement) compared with full-coverage metal-ceramic crown; GRADE not reported.

1 finding from 1 review

Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes
36 months (3 years); dislodgement assessed at 24 months
RR 1.85 [0.17, 19.8]
1 study · 104 participants
GRADE not reported

Ledermix (corticosteroid/antibiotic pulp-capping cement) vs Zinc oxide and eugenol (ZOE)

Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures

1 finding from 1 review

Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes
24 months
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
1 study · 275 participants
GRADE not reported