Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

467 questions · 495 findings · 30 reviews · Pregnancy and Childbirth

No studies found 124 · 25.1%GRADE not reported 48 · 9.7%Very low 104 · 21%Low 134 · 27.1%Moderate 62 · 12.5%High 23 · 4.6%

Acupuncture vs placebo

Perinatal mortality · Pregnant women with hyperemesis gravidarum

Acupuncture showed no clear difference in stillbirth and neonatal death compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids vs promethazine

Intervention side effects: drowsiness 48hrs and 3‐10 days · Pregnant women with hyperemesis gravidarum

Corticosteroids showed no clear difference in intervention side effects: drowsiness 48hrs and 3‐10 days compared with promethazine (low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Pregnancy complications · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes pregnancy complications compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Spontaneous abortion · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes spontaneous abortion compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Perinatal mortality · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes stillbirth and neonatal death compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Congenital abnormalities · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes congenital abnormalities compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Severity, reduction or cessation in nausea/vomiting 2. Number of episodes of emesis 3. Quality of life outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture vs metoclopramide

Reduction or cessation in nausea · Pregnant women with hyperemesis gravidarum

It is very uncertain whether acupuncture changes reduction or cessation in nausea compared with metoclopramide (very low certainty).

1 finding from 1 review

Acupuncture vs metoclopramide

Reduction or cessation in vomiting · Pregnant women with hyperemesis gravidarum

It is very uncertain whether acupuncture changes reduction or cessation in vomiting compared with metoclopramide (very low certainty).

1 finding from 1 review

Regional analgesia (with tocolysis) vs no intervention of regional analgesia (with or without tocolysis)

Caesarean section · patients with breech presentation

It is very uncertain whether regional analgesia (with tocolysis) changes caesarean section (primary) compared with no intervention of regional analgesia (with or without tocolysis) (very low certainty).

1 finding from 1 review